Mudel / Mootor	Väljalaske aasta	Võimsus	Kütus
MERCEDES-BENZ S-CLASS
MERCEDES-BENZ S-CLASS (W221) / S 63 AMG (221.077, 221.177)	10.2006 - 12.2013	386 Kw - 525 HP / M 156.984	Bensiin
MERCEDES-BENZ S-CLASS (W221) / S 600 (221.176)	12.2005 - 12.2013	380 Kw - 517 HP / M 275.953	Bensiin
MERCEDES-BENZ S-CLASS (W221) / S 400 Hybrid (221.095, 221.195)	01.2009 - 12.2013	205 Kw - 279 HP / M 272.974	Bensiin/elekter
MERCEDES-BENZ S-CLASS (W221) / S 300 (221.054, 221.154)	08.2006 - 12.2013	170 Kw - 231 HP / M 272.946	Bensiin
MERCEDES-BENZ S-CLASS (W221) / S 320 CDI (221.022, 221.122)	12.2005 - 06.2009	173 Kw - 235 HP / OM 642.930	Diisel
MERCEDES-BENZ S-CLASS (W221) / S 280 (221.054)	08.2006 - 12.2013	170 Kw - 231 HP / M 272.946	Bensiin
MERCEDES-BENZ S-CLASS (W221) / S 500 (221.071, 221.171)	10.2005 - 12.2013	285 Kw - 388 HP / M 273.961	Bensiin
MERCEDES-BENZ S-CLASS (W221) / S 420 CDI (221.028, 221.128)	10.2006 - 12.2009	235 Kw - 320 HP / OM 629.911	Diisel
MERCEDES-BENZ S-CLASS (W221) / S 350 (221.056, 221.156)	10.2005 - 12.2013	200 Kw - 272 HP / M 272.965	Bensiin
MERCEDES-BENZ S-CLASS (W221) / S 320 CDI	10.2005 - 12.2013	155 Kw - 211 HP / OM 642.930	Diisel
MERCEDES-BENZ S-CLASS (W221) / S 65 AMG (221.179)	12.2005 - 12.2013	450 Kw - 612 HP / M 275.982	Bensiin
MERCEDES-BENZ S-CLASS (W221) / S 350 CDI	06.2009 - 12.2013	173 Kw - 235 HP / OM 642.930	Diisel